CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells

Dysregulation in the extracellular matrix (ECM) microenvironment surrounding the retinal pigment epithelium (RPE) has been implicated in the etiology of proliferative vitreoretinopathy and age-related macular degeneration. The regulation of ECM remodeling by RPE cells is not well understood. We show...

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Detalles Bibliográficos
Autores principales: Hsu, Kuo-Shun, Otsu, Wataru, Li, Yao, Wang, Heuy-Ching, Chen, Shuibing, Tsang, Stephen H., Chuang, Jen-Zen, Sung, Ching-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706427/
https://www.ncbi.nlm.nih.gov/pubmed/31439888
http://dx.doi.org/10.1038/s41598-019-48438-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706427/
https://www.ncbi.nlm.nih.gov/pubmed/31439888
http://dx.doi.org/10.1038/s41598-019-48438-0

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