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Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease

Pancreatic ductal adenocarcinoma (PDA) has a highly immunosuppressive microenvironment, which is contributed by the complex interaction between cancer cells and a heterogeneous population of stromal cells. Therefore, facile and trackable models are needed for integrative and dynamic interrogation of...

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Detalles Bibliográficos
Autores principales:	Filippini, Dea, Agosto, Sabrina D’, Delfino, Pietro, Simbolo, Michele, Piro, Geny, Rusev, Borislav, Veghini, Lisa, Cantù, Cinzia, Lupo, Francesca, Ugel, Stefano, De Sanctis, Francesco, Bronte, Vincenzo, Milella, Michele, Tortora, Giampaolo, Scarpa, Aldo, Carbone, Carmine, Corbo, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706454/ https://www.ncbi.nlm.nih.gov/pubmed/31439856 http://dx.doi.org/10.1038/s41598-019-48663-7

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