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Efficient and specific oligo-based depletion of rRNA

In most organisms, ribosomal RNA (rRNA) contributes to >85% of total RNA. Thus, to obtain useful information from RNA-sequencing (RNA-seq) analyses at reasonable sequencing depth, typically, mature polyadenylated transcripts are enriched or rRNA molecules are depleted. Targeted depletion of rRNA...

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Detalles Bibliográficos
Autores principales: Kraus, Amelie J., Brink, Benedikt G., Siegel, T. Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706579/
https://www.ncbi.nlm.nih.gov/pubmed/31439880
http://dx.doi.org/10.1038/s41598-019-48692-2