Paracrine Crosstalk between Fibroblasts and ER(+) Breast Cancer Cells Creates an IL1β-Enriched Niche that Promotes Tumor Growth

Breast cancer-induced activated fibroblasts support tumor progression. However, the role of normal fibroblasts in tumor progression remains controversial. In this study, we used modified patient-derived organoid cultures and demonstrate that constitutively secreted cytokines from normal breast fibro...

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Detalles Bibliográficos
Autores principales: Chatterjee, Sumanta, Bhat, Vasudeva, Berdnikov, Alexei, Liu, Jiahui, Zhang, Guihua, Buchel, Edward, Safneck, Janice, Marshall, Aaron J., Murphy, Leigh C., Postovit, Lynne-Marie, Raouf, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706609/
https://www.ncbi.nlm.nih.gov/pubmed/31419632
http://dx.doi.org/10.1016/j.isci.2019.07.034

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