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Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of Escherichia coli During Adaptive Laboratory Evolution

Adaptive laboratory evolution (ALE) is used to find causal mutations that underlie improved strain performance under the applied selection pressure. ALE studies have revealed that mutator populations tend to outcompete their non-mutator counterparts following the evolutionary trajectory. Among them,...

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Detalles Bibliográficos
Autores principales: Kang, Minjeong, Kim, Kangsan, Choe, Donghui, Cho, Suhyung, Kim, Sun Chang, Palsson, Bernhard, Cho, Byung-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706779/
https://www.ncbi.nlm.nih.gov/pubmed/31474949
http://dx.doi.org/10.3389/fmicb.2019.01845

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