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Calbindin-D28K Limits Dopamine Release in Ventral but Not Dorsal Striatum by Regulating Ca(2+) Availability and Dopamine Transporter Function

[Image: see text] The calcium-binding protein calbindin-D28K, or calb1, is expressed at higher levels by dopamine (DA) neurons originating in the ventral tegmental area (VTA) than in the adjacent substantia nigra pars compacta (SNc). Calb1 has received attention for a potential role in neuroprotecti...

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Detalles Bibliográficos
Autores principales: Brimblecombe, Katherine R., Vietti-Michelina, Stefania, Platt, Nicola J., Kastli, Rahel, Hnieno, Ahmad, Gracie, Caitlin J., Cragg, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706870/
https://www.ncbi.nlm.nih.gov/pubmed/31361457
http://dx.doi.org/10.1021/acschemneuro.9b00325