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The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis

BACKGROUND: Age-related macular degeneration (AMD) is a multifactorial chronic disease of the eye. Several candidate pathways have been hypothesized to play a role in AMD pathogenesis. Our work and those of others suggests inflammasome activity as a mechanism associated with retinal pigment epitheli...

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Detalles Bibliográficos
Autores principales:	Gao, Jiangyuan, Cui, Jing Z., Wang, Aikun, Chen, Hao Hang Rachel, Fong, Alison, Matsubara, Joanne A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706877/ https://www.ncbi.nlm.nih.gov/pubmed/31438981 http://dx.doi.org/10.1186/s12974-019-1558-5

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