Cargando…

Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer’s disease: a preclinical study in rTg4510 mice

BACKGROUND: The lack of effective treatment options for Alzheimer’s disease (AD) is of momentous societal concern. Synaptic loss is the hallmark of AD that correlates best with impaired memory and occurs early in the disease process, before the onset of clinical symptoms. We have developed a small-m...

Descripción completa

Detalles Bibliográficos
Autores principales: Foster, Joshua B., Lashley, Rashelle, Zhao, Fangli, Wang, Xueqin, Kung, Nydia, Askwith, Candice C., Lin, Lin, Shultis, Michael W., Hodgetts, Kevin J., Lin, Chien-Liang Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706914/
https://www.ncbi.nlm.nih.gov/pubmed/31439023
http://dx.doi.org/10.1186/s13195-019-0530-z