A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells

BACKGROUND: An increasing number of anticancer agents has been proposed in recent years with the attempt to overcome treatment-resistant cancer cells and particularly cancer stem cells (CSC), the major culprits for tumour resistance and recurrence. However, a huge obstacle to treatment success is th...

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Detalles Bibliográficos
Autores principales: Orienti, Isabella, Salvati, Valentina, Sette, Giovanni, Zucchetti, Massimo, Bongiorno-Borbone, Lucilla, Peschiaroli, Angelo, Zolla, Lello, Francescangeli, Federica, Ferrari, Mariella, Matteo, Cristina, Bello, Ezia, Di Virgilio, Antonio, Falchi, Mario, De Angelis, Maria Laura, Baiocchi, Marta, Melino, Gerry, De Maria, Ruggero, Zeuner, Ann, Eramo, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706930/
https://www.ncbi.nlm.nih.gov/pubmed/31439019
http://dx.doi.org/10.1186/s13046-019-1383-9

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