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Ultra-High-Precision, in-vivo Pharmacokinetic Measurements Highlight the Need for and a Route Toward More Highly Personalized Medicine

Clinical drug dosing would, ideally, be informed by high-precision, patient-specific data on drug metabolism. The direct determination of patient-specific drug pharmacokinetics (“peaks and troughs”), however, currently relies on cumbersome, laboratory-based approaches that require hours to days to r...

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Detalles Bibliográficos
Autores principales: Vieira, Philip A., Shin, Christina B., Arroyo-Currás, Netzahualcóyotl, Ortega, Gabriel, Li, Weiwei, Keller, Arturo A., Plaxco, Kevin W., Kippin, Tod E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707041/
https://www.ncbi.nlm.nih.gov/pubmed/31475156
http://dx.doi.org/10.3389/fmolb.2019.00069