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Self-organized formation of developing appendages from murine pluripotent stem cells

Limb development starts with the formation of limb buds (LBs), which consist of tissues from two different germ layers; the lateral plate mesoderm-derived mesenchyme and ectoderm-derived surface epithelium. Here, we report means for induction of an LB-like mesenchymal/epithelial complex tissues from...

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Detalles Bibliográficos
Autores principales: Mori, Shunsuke, Sakakura, Eriko, Tsunekawa, Yuji, Hagiwara, Masaya, Suzuki, Takayuki, Eiraku, Mototsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707191/
https://www.ncbi.nlm.nih.gov/pubmed/31444329
http://dx.doi.org/10.1038/s41467-019-11702-y