Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements

Investigating the role that host erythrocyte proteins play in malaria infection is hampered by the genetic intractability of this anucleate cell. Here we report that reticulocytes derived through in vitro differentiation of an enucleation-competent immortalized erythroblast cell line (BEL-A) support...

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Detalles Bibliográficos
Autores principales: Satchwell, Timothy J., Wright, Katherine E., Haydn-Smith, Katy L., Sánchez-Román Terán, Fernando, Moura, Pedro L., Hawksworth, Joseph, Frayne, Jan, Toye, Ashley M., Baum, Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707200/
https://www.ncbi.nlm.nih.gov/pubmed/31444345
http://dx.doi.org/10.1038/s41467-019-11790-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707200/
https://www.ncbi.nlm.nih.gov/pubmed/31444345
http://dx.doi.org/10.1038/s41467-019-11790-w

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