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Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements
Investigating the role that host erythrocyte proteins play in malaria infection is hampered by the genetic intractability of this anucleate cell. Here we report that reticulocytes derived through in vitro differentiation of an enucleation-competent immortalized erythroblast cell line (BEL-A) support...
Autores principales: | Satchwell, Timothy J., Wright, Katherine E., Haydn-Smith, Katy L., Sánchez-Román Terán, Fernando, Moura, Pedro L., Hawksworth, Joseph, Frayne, Jan, Toye, Ashley M., Baum, Jake |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707200/ https://www.ncbi.nlm.nih.gov/pubmed/31444345 http://dx.doi.org/10.1038/s41467-019-11790-w |
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