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hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy

Acute myeloid leukemia (AML) is a genetically heterogeneous malignant disorder of the hematopoietic system, characterized by the accumulation of DNA-damaged immature myeloid precursors. Here, we find that hCINAP is involved in the repair of double-stranded DNA breaks (DSB) and that its expression co...

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Detalles Bibliográficos
Autores principales:	Xu, Ruidan, Yu, Shuyu, Zhu, Dan, Huang, Xinping, Xu, Yuqi, Lao, Yimin, Tian, Yonglu, Zhang, Jinfang, Tang, Zefang, Zhang, Zemin, Yi, Jing, Zhu, Hong-Hu, Zheng, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707248/ https://www.ncbi.nlm.nih.gov/pubmed/31444354 http://dx.doi.org/10.1038/s41467-019-11795-5

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