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Constitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis

Aerobic exercise prevents age-dependent decline in cognition and hippocampal neurogenesis. The transcription factor peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1α) mediates many of the exercise-induced benefits in skeletal muscle, including the release of factors into...

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Detalles Bibliográficos
Autores principales:	Karlsson, Lars, González-Alvarado, María Nazareth, Motalleb, Reza, Blomgren, Klas, Börjesson, Mats, Kuhn, Hans Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707251/ https://www.ncbi.nlm.nih.gov/pubmed/31444397 http://dx.doi.org/10.1038/s41598-019-48795-w

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