A high-sugar diet rapidly enhances susceptibility to colitis via depletion of luminal short-chain fatty acids in mice

Western-style diets have been implicated in triggering inflammatory bowel disease activity. The aim of this study was to identify the effect of a short-term diet high in sugar on susceptibility to colitis. Adult wild-type mice were placed on chow or a high sugar diet (50% sucrose) ± acetate. After t...

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Detalles Bibliográficos
Autores principales: Laffin, Michael, Fedorak, Robert, Zalasky, Aiden, Park, Heekuk, Gill, Amanpreet, Agrawal, Ambika, Keshteli, Ammar, Hotte, Naomi, Madsen, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707253/
https://www.ncbi.nlm.nih.gov/pubmed/31444382
http://dx.doi.org/10.1038/s41598-019-48749-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707253/
https://www.ncbi.nlm.nih.gov/pubmed/31444382
http://dx.doi.org/10.1038/s41598-019-48749-2

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