Sequential adjustment of cytotoxic T lymphocyte densities improves efficacy in controlling tumor growth

Understanding the human cytotoxic T lymphocyte (CTL) biology is crucial to develop novel strategies aiming at maximizing their lytic capacity against cancer cells. Here we introduce an agent-based model, calibrated on population-scale experimental data that allows quantifying human CTL per capita ki...

Descripción completa

Detalles Bibliográficos
Autores principales: Khazen, Roxana, Müller, Sabina, Lafouresse, Fanny, Valitutti, Salvatore, Cussat-Blanc, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707257/
https://www.ncbi.nlm.nih.gov/pubmed/31444380
http://dx.doi.org/10.1038/s41598-019-48711-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707257/
https://www.ncbi.nlm.nih.gov/pubmed/31444380
http://dx.doi.org/10.1038/s41598-019-48711-2

Ejemplares similares