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Sequential adjustment of cytotoxic T lymphocyte densities improves efficacy in controlling tumor growth
Understanding the human cytotoxic T lymphocyte (CTL) biology is crucial to develop novel strategies aiming at maximizing their lytic capacity against cancer cells. Here we introduce an agent-based model, calibrated on population-scale experimental data that allows quantifying human CTL per capita ki...
Autores principales: | Khazen, Roxana, Müller, Sabina, Lafouresse, Fanny, Valitutti, Salvatore, Cussat-Blanc, Sylvain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707257/ https://www.ncbi.nlm.nih.gov/pubmed/31444380 http://dx.doi.org/10.1038/s41598-019-48711-2 |
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