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A co-expressed gene status of adenylate kinase 1/4 reveals prognostic gene signature associated with prognosis and sensitivity to EGFR targeted therapy in lung adenocarcinoma

Cancer cells utilize altered bioenergetics to fuel uncontrolled proliferation and progression. At the core of bioenergetics, adenine nucleotides are the building blocks for nucleotide synthesis, energy transfer and diverse metabolic processes. Adenylate kinases (AK) are ubiquitous phosphotransferase...

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Detalles Bibliográficos
Autores principales: Jan, Yi-Hua, Lai, Tsung-Ching, Yang, Chih-Jen, Huang, Ming-Shyan, Hsiao, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707279/
https://www.ncbi.nlm.nih.gov/pubmed/31444368
http://dx.doi.org/10.1038/s41598-019-48243-9

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