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A co-expressed gene status of adenylate kinase 1/4 reveals prognostic gene signature associated with prognosis and sensitivity to EGFR targeted therapy in lung adenocarcinoma
Cancer cells utilize altered bioenergetics to fuel uncontrolled proliferation and progression. At the core of bioenergetics, adenine nucleotides are the building blocks for nucleotide synthesis, energy transfer and diverse metabolic processes. Adenylate kinases (AK) are ubiquitous phosphotransferase...
Autores principales: | Jan, Yi-Hua, Lai, Tsung-Ching, Yang, Chih-Jen, Huang, Ming-Shyan, Hsiao, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707279/ https://www.ncbi.nlm.nih.gov/pubmed/31444368 http://dx.doi.org/10.1038/s41598-019-48243-9 |
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