Microenvironment meets lineage complexity in junctional tumorigenesis

Using a sensitizing genetic model, Moon and colleagues provide compelling data for a determinant role of microenvironment in tumorigenesis, and lend support to the notion that such influences can be pharmacologically dampened to reduce the onset of cancers.

Detalles Bibliográficos
Autores principales: Xian, Wa, McKeon, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707302/
https://www.ncbi.nlm.nih.gov/pubmed/31444324
http://dx.doi.org/10.1038/s41467-019-11651-6
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author Xian, Wa
McKeon, Frank
author_facet Xian, Wa
McKeon, Frank
author_sort Xian, Wa
collection PubMed
description Using a sensitizing genetic model, Moon and colleagues provide compelling data for a determinant role of microenvironment in tumorigenesis, and lend support to the notion that such influences can be pharmacologically dampened to reduce the onset of cancers.
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spelling pubmed-67073022019-08-26 Microenvironment meets lineage complexity in junctional tumorigenesis Xian, Wa McKeon, Frank Nat Commun Comment Using a sensitizing genetic model, Moon and colleagues provide compelling data for a determinant role of microenvironment in tumorigenesis, and lend support to the notion that such influences can be pharmacologically dampened to reduce the onset of cancers. Nature Publishing Group UK 2019-08-23 /pmc/articles/PMC6707302/ /pubmed/31444324 http://dx.doi.org/10.1038/s41467-019-11651-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Comment
Xian, Wa
McKeon, Frank
Microenvironment meets lineage complexity in junctional tumorigenesis
title Microenvironment meets lineage complexity in junctional tumorigenesis
title_full Microenvironment meets lineage complexity in junctional tumorigenesis
title_fullStr Microenvironment meets lineage complexity in junctional tumorigenesis
title_full_unstemmed Microenvironment meets lineage complexity in junctional tumorigenesis
title_short Microenvironment meets lineage complexity in junctional tumorigenesis
title_sort microenvironment meets lineage complexity in junctional tumorigenesis
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707302/
https://www.ncbi.nlm.nih.gov/pubmed/31444324
http://dx.doi.org/10.1038/s41467-019-11651-6
work_keys_str_mv AT xianwa microenvironmentmeetslineagecomplexityinjunctionaltumorigenesis
AT mckeonfrank microenvironmentmeetslineagecomplexityinjunctionaltumorigenesis

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