Cargando…

GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway

BACKGROUND: Increasing evidence suggests that glutathione peroxidase 2 (GPX2) plays important roles in the tumorigenesis and progression of various human cancers, such as colorectal carcinomas and lung adenocarcinomas. However, the role of GPX2 in cervical cancer is unclear. In this study, we identi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yingxin, Cao, Penglong, Alshwmi, Mohammed, Jiang, Nan, Xiao, Zhen, Jiang, Fengquan, Gu, Juebin, Wang, Xiaonan, Sun, Xiaoye, Li, Shijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707354/ https://www.ncbi.nlm.nih.gov/pubmed/31695405 http://dx.doi.org/10.2147/OTT.S208781

Ejemplares similares

GPX2 predicts recurrence-free survival and triggers the Wnt/β-catenin/EMT pathway in prostate cancer
por: Yang, Ming, et al.
Publicado: (2022)

Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer
por: Wang, Yue, et al.
Publicado: (2022)

WDR74 promotes proliferation and metastasis in colorectal cancer cells through regulating the Wnt/β-catenin signaling pathway
por: Cai, Zhou, et al.
Publicado: (2021)

LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer
por: Cheng, Zhengyan, et al.
Publicado: (2023)

Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium
por: Chu, Fong-Fong, et al.
Publicado: (2016)

Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/β-Catenin Signaling Pathway
por: Lan, Kangyun, et al.
Publicado: (2017)

Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/β-catenin signaling
por: Lin, Jie, et al.
Publicado: (2017)

Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation
por: Liu, Yiting, et al.
Publicado: (2023)

Role of Wnt/β-catenin pathway in inducing autophagy and apoptosis in multiple myeloma cells
por: Su, Nan, et al.
Publicado: (2016)

WNT2 Promotes Cervical Carcinoma Metastasis and Induction of Epithelial-Mesenchymal Transition
por: Zhou, Yun, et al.
Publicado: (2016)

Inhibition of the PIN1-NRF2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells: PIN1/NRF2/GPX4 axis in CC
por: Zhang, Zheng, et al.
Publicado: (2022)

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
por: Jung, Youn-Sang, et al.
Publicado: (2015)

β-Arrestin 1/2 Aggravates Podocyte Apoptosis of Diabetic Nephropathy via Wnt/β-Catenin Pathway
por: Wang, Yao, et al.
Publicado: (2018)

IC-2 Suppresses Proliferation and Induces Apoptosis of Bladder Cancer Cells via the Wnt/β-Catenin Pathway
por: Wu, Lingfeng, et al.
Publicado: (2018)

CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2
por: Feng, Dingqing, et al.
Publicado: (2020)

SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4
por: Cheng, Lulin, et al.
Publicado: (2023)

FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β-catenin pathway
por: Liu, Peng, et al.
Publicado: (2023)

GPX2 promotes development of bladder cancer with squamous cell differentiation through the control of apoptosis
por: Naiki, Taku, et al.
Publicado: (2018)

Calpain2 Upregulation Regulates EMT-Mediated Pancreatic Cancer Metastasis via the Wnt/β-Catenin Signaling Pathway
por: Peng, Xiulan, et al.
Publicado: (2022)

APMAP Promotes Epithelial-Mesenchymal Transition and Metastasis of Cervical Cancer Cells by Activating the Wnt/β-catenin Pathway
por: Zhu, Xiuting, et al.
Publicado: (2021)

Wnt and β-Catenin Signaling in the Bone Metastasis of Prostate Cancer
por: Kaplan, Zachary, et al.
Publicado: (2021)

NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6
por: Xu, Chunjie, et al.
Publicado: (2019)

The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury
por: Chen, Zongyu, et al.
Publicado: (2023)

COL5A2 Inhibits the TGF-β and Wnt/β-Catenin Signaling Pathways to Inhibit the Invasion and Metastasis of Osteosarcoma
por: Han, Yan-Long, et al.
Publicado: (2022)

EZH2 inhibition promotes methyl jasmonate-induced apoptosis of human colorectal cancer through the Wnt/β-catenin pathway
por: Wang, Yao, et al.
Publicado: (2021)

GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma
por: Tan, Wenliang, et al.
Publicado: (2022)

PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation
por: Chen, Xin, et al.
Publicado: (2023)

Lnc-MAP6-1:3 knockdown inhibits osteosarcoma progression by modulating Bax/Bcl-2 and Wnt/β-catenin pathways
por: Lin, Hao, et al.
Publicado: (2020)

SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex
por: Zhao, S-J, et al.
Publicado: (2018)

Nucleolar and spindle associated protein 1 promotes metastasis of cervical carcinoma cells by activating Wnt/β-catenin signaling
por: Li, Han, et al.
Publicado: (2019)

Alpha-2 Heremans Schmid Glycoprotein (AHSG) promotes the proliferation of bladder cancer cells by regulating the TGF-β signalling pathway
por: Dong, Yufei, et al.
Publicado: (2022)

miR‑149‑3p suppresses the proliferation and metastasis of glioma cells by targeting the CBX2/Wnt/β‑catenin pathway
por: Wang, Yanjun, et al.
Publicado: (2023)

Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility
por: Wang, Bingqi, et al.
Publicado: (2020)

Activation of Intracellular Calcium by Multiple Wnt Ligands and Translocation of β-Catenin into the Nucleus: A CONVERGENT MODEL OF Wnt/Ca(2+) AND Wnt/β-CATENIN PATHWAYS
por: Thrasivoulou, Christopher, et al.
Publicado: (2013)

Intravital imaging of Wnt/β-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis
por: Stoletov, Konstantin, et al.
Publicado: (2023)

Curcumin Inhibits Cell Viability and Increases Apoptosis of SW620 Human Colon Adenocarcinoma Cells via the Caudal Type Homeobox-2 (CDX2)/Wnt/β-Catenin Pathway
por: Jiang, Xinger, et al.
Publicado: (2019)

Overexpression of NELFE contributes to gastric cancer progression via Wnt/β-catenin signaling-mediated activation of CSNK2B expression
por: Yu, Shijun, et al.
Publicado: (2021)

KIF18B promotes tumor progression through activating the Wnt/β-catenin pathway in cervical cancer
por: Wu, Yaqin, et al.
Publicado: (2018)

LDLRAD2 overexpression predicts poor prognosis and promotes metastasis by activating Wnt/β-catenin/EMT signaling cascade in gastric cancer
por: Wei, Yucai, et al.
Publicado: (2019)

Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin
por: Xiao, Jialing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r5ucj1kpfskobebvmis8nnl95o