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An RDAU-NET model for lesion segmentation in breast ultrasound images

Breast cancer is a common gynecological disease that poses a great threat to women health due to its high malignant rate. Breast cancer screening tests are used to find any warning signs or symptoms for early detection and currently, Ultrasound screening is the preferred method for breast cancer dia...

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Autores principales: Zhuang, Zhemin, Li, Nan, Joseph Raj, Alex Noel, Mahesh, Vijayalakshmi G. V., Qiu, Shunmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707567/
https://www.ncbi.nlm.nih.gov/pubmed/31442268
http://dx.doi.org/10.1371/journal.pone.0221535
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author Zhuang, Zhemin
Li, Nan
Joseph Raj, Alex Noel
Mahesh, Vijayalakshmi G. V.
Qiu, Shunmin
author_facet Zhuang, Zhemin
Li, Nan
Joseph Raj, Alex Noel
Mahesh, Vijayalakshmi G. V.
Qiu, Shunmin
author_sort Zhuang, Zhemin
collection PubMed
description Breast cancer is a common gynecological disease that poses a great threat to women health due to its high malignant rate. Breast cancer screening tests are used to find any warning signs or symptoms for early detection and currently, Ultrasound screening is the preferred method for breast cancer diagnosis. The localization and segmentation of the lesions in breast ultrasound (BUS) images are helpful for clinical diagnosis of the disease. In this paper, an RDAU-NET (Residual-Dilated-Attention-Gate-UNet) model is proposed and employed to segment the tumors in BUS images. The model is based on the conventional U-Net, but the plain neural units are replaced with residual units to enhance the edge information and overcome the network performance degradation problem associated with deep networks. To increase the receptive field and acquire more characteristic information, dilated convolutions were used to process the feature maps obtained from the encoder stages. The traditional cropping and copying between the encoder-decoder pipelines were replaced by the Attention Gate modules which enhanced the learning capabilities through suppression of background information. The model, when tested with BUS images with benign and malignant tumor presented excellent segmentation results as compared to other Deep Networks. A variety of quantitative indicators including Accuracy, Dice coefficient, AUC(Area-Under-Curve), Precision, Sensitivity, Specificity, Recall, F1score and M-IOU (Mean-Intersection-Over-Union) provided performances above 80%. The experimental results illustrate that the proposed RDAU-NET model can accurately segment breast lesions when compared to other deep learning models and thus has a good prospect for clinical diagnosis.
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spelling pubmed-67075672019-09-04 An RDAU-NET model for lesion segmentation in breast ultrasound images Zhuang, Zhemin Li, Nan Joseph Raj, Alex Noel Mahesh, Vijayalakshmi G. V. Qiu, Shunmin PLoS One Research Article Breast cancer is a common gynecological disease that poses a great threat to women health due to its high malignant rate. Breast cancer screening tests are used to find any warning signs or symptoms for early detection and currently, Ultrasound screening is the preferred method for breast cancer diagnosis. The localization and segmentation of the lesions in breast ultrasound (BUS) images are helpful for clinical diagnosis of the disease. In this paper, an RDAU-NET (Residual-Dilated-Attention-Gate-UNet) model is proposed and employed to segment the tumors in BUS images. The model is based on the conventional U-Net, but the plain neural units are replaced with residual units to enhance the edge information and overcome the network performance degradation problem associated with deep networks. To increase the receptive field and acquire more characteristic information, dilated convolutions were used to process the feature maps obtained from the encoder stages. The traditional cropping and copying between the encoder-decoder pipelines were replaced by the Attention Gate modules which enhanced the learning capabilities through suppression of background information. The model, when tested with BUS images with benign and malignant tumor presented excellent segmentation results as compared to other Deep Networks. A variety of quantitative indicators including Accuracy, Dice coefficient, AUC(Area-Under-Curve), Precision, Sensitivity, Specificity, Recall, F1score and M-IOU (Mean-Intersection-Over-Union) provided performances above 80%. The experimental results illustrate that the proposed RDAU-NET model can accurately segment breast lesions when compared to other deep learning models and thus has a good prospect for clinical diagnosis. Public Library of Science 2019-08-23 /pmc/articles/PMC6707567/ /pubmed/31442268 http://dx.doi.org/10.1371/journal.pone.0221535 Text en © 2019 Zhuang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zhuang, Zhemin
Li, Nan
Joseph Raj, Alex Noel
Mahesh, Vijayalakshmi G. V.
Qiu, Shunmin
An RDAU-NET model for lesion segmentation in breast ultrasound images
title An RDAU-NET model for lesion segmentation in breast ultrasound images
title_full An RDAU-NET model for lesion segmentation in breast ultrasound images
title_fullStr An RDAU-NET model for lesion segmentation in breast ultrasound images
title_full_unstemmed An RDAU-NET model for lesion segmentation in breast ultrasound images
title_short An RDAU-NET model for lesion segmentation in breast ultrasound images
title_sort rdau-net model for lesion segmentation in breast ultrasound images
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707567/
https://www.ncbi.nlm.nih.gov/pubmed/31442268
http://dx.doi.org/10.1371/journal.pone.0221535
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