Cargando…

Synergistic effect of nano-selenium and metformin on type 2 diabetic rat model: Diabetic complications alleviation through insulin sensitivity, oxidative mediators and inflammatory markers

BACKGROUND AND OBJECTIVES: In the present article, we explore a novel strategy of selenium nanoparticles (Se-NPs) for the treatment of type 2 diabetes mellitus (T2DM) by investigating the effect of Se-NPs alone and in combination with standard anti-diabetic drug metformin (MET) in high-fat diet/stre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdulmalek, Shaymaa A., Balbaa, Mahmoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707613/ https://www.ncbi.nlm.nih.gov/pubmed/31442295 http://dx.doi.org/10.1371/journal.pone.0220779

Ejemplares similares

Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs
por: Balbaa, Mahmoud, et al.
Publicado: (2017)

Therapeutic Screening of Herbal Remedies for the Management of Diabetes
por: Balbaa, Mahmoud, et al.
Publicado: (2021)

Ameliorative effect of curcumin and zinc oxide nanoparticles on multiple mechanisms in obese rats with induced type 2 diabetes
por: Abdulmalek, Shaymaa, et al.
Publicado: (2021)

Protective Effect of Natural Antioxidant, Curcumin Nanoparticles, and Zinc Oxide Nanoparticles against Type 2 Diabetes-Promoted Hippocampal Neurotoxicity in Rats
por: Abdulmalek, Shaymaa, et al.
Publicado: (2021)

Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity
por: Bruckbauer, Antje, et al.
Publicado: (2013)

Bee venom-loaded EGFR-targeting peptide-coupled chitosan nanoparticles for effective therapy of hepatocellular carcinoma by inhibiting EGFR-mediated MEK/ERK pathway
por: Abdulmalek, Shaymaa, et al.
Publicado: (2022)

Effects of insulin aspart and metformin on gestational diabetes mellitus and inflammatory markers
por: Wang, Yan, et al.
Publicado: (2023)

Rapamycin/metformin co‐treatment normalizes insulin sensitivity and reduces complications of metabolic syndrome in type 2 diabetic mice
por: Reifsnyder, Peter C., et al.
Publicado: (2022)

Anti-diabetic activity of different oils through their effect on arylsulfatases
por: Samarji, Rima, et al.
Publicado: (2014)

Role of selenium in type 2 diabetes, insulin resistance and insulin secretion
por: Casanova, Pilar, et al.
Publicado: (2023)

Modulation of autophagy, apoptosis and oxidative stress: a clue for repurposing metformin in photoaging
por: Mostafa, Dalia Kamal, et al.
Publicado: (2022)

Nigella sativa Relieves the Altered Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats Fed with a High-Fat Diet
por: Balbaa, Mahmoud, et al.
Publicado: (2016)

Comparative evaluation of the therapeutic effect of metformin monotherapy with metformin and acupuncture combined therapy on weight loss and insulin sensitivity in diabetic patients
por: Firouzjaei, A, et al.
Publicado: (2016)

Combination Therapy with Oleanolic Acid and Metformin as a Synergistic Treatment for Diabetes
por: Wang, Xue, et al.
Publicado: (2015)

Early Diabetic Nephropathy: A complication of reduced insulin sensitivity in type 1 diabetes
por: Bjornstad, Petter, et al.
Publicado: (2013)

Exosomes as Promising Nanostructures in Diabetes Mellitus: From Insulin Sensitivity to Ameliorating Diabetic Complications
por: Ashrafizadeh, Milad, et al.
Publicado: (2022)

Exogenous application of selenium and nano-selenium alleviates salt stress and improves secondary metabolites in lemon verbena under salinity stress
por: Ghanbari, Fardin, et al.
Publicado: (2023)

Are There Differences in Gut Microbiome in Patients with Type 2 Diabetes Treated by Metformin or Metformin and Insulin?
por: Dzięgielewska-Gęsiak, Sylwia, et al.
Publicado: (2022)

Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats
por: Abd El-Hakim, Yasmina M., et al.
Publicado: (2020)

Metformin and Canagliflozin Are Equally Renoprotective in Diabetic Kidney Disease but Have No Synergistic Effect
por: Corremans, Raphaëlle, et al.
Publicado: (2023)

Diabetes and Insulin Therapy, but Not Metformin, Are Related to Hepatocellular Cancer Risk
por: Miele, Luca, et al.
Publicado: (2015)

Could Metformin Manage Gestational Diabetes Mellitus instead of Insulin?
por: Saleh, Hend S., et al.
Publicado: (2016)

Metformin Alleviates Diabetes-Associated Hypertension by Attenuating the Renal Epithelial Sodium Channel
por: Scindia, Yogesh M., et al.
Publicado: (2023)

Maternal and Neonatal Circulating Markers of Metabolic and Cardiovascular Risk in the Metformin in Gestational Diabetes (MiG) Trial: Responses to maternal metformin versus insulin treatment
por: Barrett, Helen L., et al.
Publicado: (2013)

Effects of insulin and metformin on fetal kidney development of streptozotocin-induced gestational diabetic albino rats
por: Kassab, Ban M., et al.
Publicado: (2019)

Effects of Exenatide Plus Rosiglitazone on β-Cell Function and Insulin Sensitivity in Subjects With Type 2 Diabetes on Metformin
por: DeFronzo, Ralph A., et al.
Publicado: (2010)

Protective role of nano-selenium-enriched Bifidobacterium longum in delaying the onset of streptozotocin-induced diabetes
por: Lin, Yan, et al.
Publicado: (2018)

Senolytics: Potential for Alleviating Diabetes and Its Complications
por: Palmer, Allyson K, et al.
Publicado: (2021)

Selenium Supranutrition: Are the Potential Benefits of Chemoprevention Outweighed by the Promotion of Diabetes and Insulin Resistance?
por: Rocourt, Caroline R. B., et al.
Publicado: (2013)

Zinc and curcumin lower arylsulfatses and some metabolic parameters in streptozotocin-induced diabetes
por: Balbaa, Mahmoud, et al.
Publicado: (2017)

Effect of hydroxychloroquine on beta cell function, insulin resistance, and inflammatory markers in type 2 diabetes patients uncontrolled on glimepiride and metformin therapy
por: Rajput, Rajesh, et al.
Publicado: (2023)

Metformin and Cancer Occurrence in Insulin-Treated Type 2 Diabetic Patients
por: Monami, Matteo, et al.
Publicado: (2011)

Metformin vs Insulin in the Management of Gestational Diabetes: A Meta-Analysis
por: Gui, Juan, et al.
Publicado: (2013)

Metformin improves diabetic kidney disease
por: Beladi Mousavi, Seyed Seifollah, et al.
Publicado: (2012)

Comment on: TODAY Study Group. Effects of Metformin, Metformin Plus Rosiglitazone, and Metformin Plus Lifestyle on Insulin Sensitivity and β-Cell Function in TODAY. Diabetes Care 2013;36:1749–1757
por: Baldi, James C., et al.
Publicado: (2013)

KDP, a Lactobacilli Product from Kimchi, Enhances Mucosal Immunity by Increasing Secretory IgA in Mice and Exhibits Antimicrobial Activity
por: Ghoneum, Mamdooh, et al.
Publicado: (2021)

The role of selenium and nano selenium on physiological responses in plant: a review
por: Khan, Zesmin, et al.
Publicado: (2023)

Effects of Metformin, Metformin Plus Rosiglitazone, and Metformin Plus Lifestyle on Insulin Sensitivity and β-Cell Function in TODAY
Publicado: (2013)

Sitagliptin/Metformin Versus Insulin Glargine Combined With Metformin in Obese Subjects With Newly Diagnosed Type 2 Diabetes
por: Ji, Ming, et al.
Publicado: (2016)

Response to Article “Are There Differences in Gut Microbiome in Patients with Type 2 Diabetes Treated by Metformin or Metformin and Insulin?” [Letter]
por: Panjaitan, Novaria Sari Dewi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_juhebdd87g45d2npv32tflf15e