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Hepatic SIRT3 Upregulation in Response to Chronic Alcohol Consumption Contributes to Alcoholic Liver Disease in Mice

BACKGROUND: Alcoholic liver disease (ALD) is a type of chronic liver disease caused by chronic ethanol overconsumption. The pathogenesis of ALD is complex and there is no effective clinical treatment thus far. SIRT3 is an NAD(+)-dependent deacetylase primarily located inside mitochondria, and report...

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Detalles Bibliográficos
Autores principales:	Ma, Yue, Chai, Hui, Ding, Qinchao, Qian, Qianyu, Yan, Zhaoyuan, Ding, Bin, Dou, Xiaobing, Li, Songtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707764/ https://www.ncbi.nlm.nih.gov/pubmed/31474877 http://dx.doi.org/10.3389/fphys.2019.01042

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