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Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis

Cancer-associated systemic inflammation is strongly linked with poor disease outcome in cancer patients(1,2). For most human epithelial tumour types, high systemic neutrophil-to-lymphocyte ratios are associated with poor overall survival(3), and experimental studies have demonstrated a causal relati...

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Detalles Bibliográficos
Autores principales:	Wellenstein, Max D., Coffelt, Seth B., Duits, Danique E.M., van Miltenburg, Martine H., Slagter, Maarten, de Rink, Iris, Henneman, Linda, Kas, Sjors M., Prekovic, Stefan, Hau, Cheei-Sing, Vrijland, Kim, Drenth, Anne Paulien, de Korte-Grimmerink, Renske, Schut, Eva, van der Heijden, Ingrid, Zwart, Wilbert, Wessels, Lodewyk F.A., Schumacher, Ton N., Jonkers, Jos, de Visser, Karin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707815/ https://www.ncbi.nlm.nih.gov/pubmed/31367040 http://dx.doi.org/10.1038/s41586-019-1450-6

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