Genetic compensation triggered by mutant mRNA degradation

Genetic robustness, or the ability of an organism to maintain fitness in the presence of mutations, can be achieved via protein feedback loops. Recent evidence suggests that organisms may also respond to mutations by upregulating related gene(s) independently of protein feedback loops, a phenomenon...

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Detalles Bibliográficos
Autores principales: El-Brolosy, Mohamed A., Kontarakis, Zacharias, Rossi, Andrea, Kuenne, Carsten, Günther, Stefan, Fukuda, Nana, Kikhi, Khrievono, Boezio, Giulia L.M., Takacs, Carter, Lai, Shih-Lei, Fukuda, Ryuichi, Gerri, Claudia, Giraldez, Antonio J., Stainier, Didier Y.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707827/
https://www.ncbi.nlm.nih.gov/pubmed/30944477
http://dx.doi.org/10.1038/s41586-019-1064-z

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