Cargando…

Structural basis for neutralization of P. vivax by naturally-acquired human antibodies that target DBP

The Plasmodium vivax Duffy binding protein (DBP) is a prime target of the protective immune response and a promising vaccine candidate for P. vivax malaria. Naturally acquired immunity (NAI) protects against malaria in adults residing in infection-endemic regions, and the passive transfer of malaria...

Descripción completa

Detalles Bibliográficos
Autores principales:	Urusova, Darya, Carias, Lenore, Huang, Yining, Nicolete, Vanessa C., Popovici, Jean, Roesch, Camille, Salinas, Nichole D., Witkowski, Benoit, Ferreira, Marcelo U., Adams, John H., Gross, Michael L., King, Christopher L., Tolia, Niraj H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707876/ https://www.ncbi.nlm.nih.gov/pubmed/31133752 http://dx.doi.org/10.1038/s41564-019-0461-2

Ejemplares similares

Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity
por: Popovici, Jean, et al.
Publicado: (2020)

Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design
por: Chen, Edwin, et al.
Publicado: (2015)

Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC
por: Batchelor, Joseph D., et al.
Publicado: (2014)

Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC
por: Batchelor, Joseph D., et al.
Publicado: (2011)

An engineered vaccine of the Plasmodium vivax Duffy binding protein enhances induction of broadly neutralizing antibodies
por: Ntumngia, Francis B., et al.
Publicado: (2017)

Impact of the first-line treatment shift from dihydroartemisinin/piperaquine to artesunate/mefloquine on Plasmodium vivax drug susceptibility in Cambodia
por: Roesch, Camille, et al.
Publicado: (2020)

Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175
por: Chen, Edwin, et al.
Publicado: (2013)

The enigmatic mechanisms by which Plasmodium vivax infects Duffy-negative individuals
por: Popovici, Jean, et al.
Publicado: (2020)

Inhibition of a malaria host–pathogen interaction by a computationally designed inhibitor
por: Tobin, Autumn R., et al.
Publicado: (2023)

Structural patterns of selection and diversity for Plasmodium vivax antigens DBP and AMA1
por: Guy, Andrew J., et al.
Publicado: (2018)

Critical Glycosylated Residues in Exon Three of Erythrocyte Glycophorin A Engage Plasmodium falciparum EBA-175 and Define Receptor Specificity
por: Salinas, Nichole D., et al.
Publicado: (2014)

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3
por: Posfai, Dora, et al.
Publicado: (2020)

Is the single variant form of Plasmodium vivax Duffy binding protein-II (PvDBP-II) adequate for inclusion in a PvDBP-II-based vaccine?
por: Valizadeh, Vahideh, et al.
Publicado: (2014)

Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response
por: Dickey, Thayne H., et al.
Publicado: (2022)

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion
por: Patel, Palak N., et al.
Publicado: (2022)

Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA
por: Wurm, Jan Philip
Publicado: (2023)

Structural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome
por: Wurm, Jan Philip, et al.
Publicado: (2021)

Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters
por: Popovici, Jean, et al.
Publicado: (2021)

Human monoclonal antibodies inhibit invasion of transgenic Plasmodium knowlesi expressing Plasmodium vivax Duffy binding protein
por: Watson, Quentin D., et al.
Publicado: (2023)

Naturally acquired antibodies to gametocyte antigens are associated with reduced transmission of Plasmodium vivax gametocytes to Anopheles arabiensis mosquitoes
por: Tebeje, Surafel K., et al.
Publicado: (2023)

Immunological characterization of a VIR protein family member (VIR-14) in Plasmodium vivax-infected subjects from different epidemiological regions in Africa and South America
por: Fantin, Raianna F., et al.
Publicado: (2023)

Targeting a Reticulocyte Binding Protein and Duffy Binding Protein to Inhibit Reticulocyte Invasion by Plasmodium vivax
por: Gupta, Sonal, et al.
Publicado: (2018)

SAT-234 DBP Gene Polymorphisms in Adult and Postmenopausal Women: Association with DBP and Vitamin D Serum Levels
por: Santos, Betânia, et al.
Publicado: (2019)

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines
por: Dickey, Thayne H., et al.
Publicado: (2023)

Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration
por: Kumar, Hirdesh, et al.
Publicado: (2022)

Antibodies to Cryptic Epitopes in Distant Homologues Underpin a Mechanism of Heterologous Immunity between Plasmodium vivax PvDBP and Plasmodium falciparum VAR2CSA
por: Mitran, Catherine J., et al.
Publicado: (2019)

Extensive genetic diversity of Plasmodium vivax dbp-II in Rio de Janeiro Atlantic Forest and Brazilian Amazon Basin: evidence of positive selection
por: Almeida-de-Oliveira, Natália Ketrin, et al.
Publicado: (2020)

Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion
por: Paing, May M, et al.
Publicado: (2018)

Home discharge and management in severe DBP patient
por: Fiorini, Patrizio
Publicado: (2015)

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption
por: Jimah, John R, et al.
Publicado: (2016)

Biodegradation of endocrine disruptor dibutyl phthalate (DBP) by a newly isolated Methylobacillus sp. V29b and the DBP degradation pathway
por: Kumar, Vinay, et al.
Publicado: (2016)

Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion
por: Roesch, Camille, et al.
Publicado: (2018)

DRINKING WATER QUALITY: Better Biomarker of DBP Exposure
por: Spivey, Angela
Publicado: (2009)

Genetic diversity and the ensuing strain specific immunity to asexual erythrocytic stage vaccine candidate antigens, MSP-1, AMA-1 and DBP, of Plasmodium vivax in Sri Lanka
por: Udagama-Randeniya, Preethi, et al.
Publicado: (2010)

Naturally-acquired and Vaccine-induced Human Monoclonal Antibodies to Plasmodium vivax Duffy Binding Protein Inhibit Invasion of Plasmodium knowlesi (PvDBPOR) Transgenic Parasites
por: Watson, Quentin D., et al.
Publicado: (2023)

The molecular basis of antimalarial drug resistance in Plasmodium vivax
por: Buyon, Lucas E., et al.
Publicado: (2021)

Characterization of P. vivax blood stage transcriptomes from field isolates reveals similarities among infections and complex gene isoforms
por: Kim, Adam, et al.
Publicado: (2017)

A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle
por: Salinas, Nichole D., et al.
Publicado: (2023)

Gle1 is required for tRNA to stimulate Dbp5 ATPase activity in vitro and to promote Dbp5 mediated tRNA export in vivo
por: Rajan, Arvind Arul Nambi, et al.
Publicado: (2023)

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA
por: Ma, Rui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lv9mt770741caoiiclvmd9m49u