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Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma

Fibrolamellar hepatocellular carcinomas (FL-HCCs) possess a unique mutation that encodes a chimeric form of protein kinase A (DNAJ-PKAc), which includes a chaperonin binding domain. DNAJ-PKAc retains most of the biochemical properties of the native enzyme, however, and activity remains dependent on...

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Detalles Bibliográficos
Autores principales:	Riehle, Kimberly J., Kenerson, Heidi L., Riggle, Kevin M., Turnham, Rigney, Sullivan, Kevin, Bauer, Renay, Scott, John D., Yeung, Raymond S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707953/ https://www.ncbi.nlm.nih.gov/pubmed/31489118 http://dx.doi.org/10.18632/oncotarget.27149

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