Inhibition of Bruton’s Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer’s Disease

Bruton’s tyrosine kinase (BTK), a critical component of B cell receptor signaling, has recently been implicated in regulation of the peripheral innate immune response. However, the role of BTK in microglia, the resident innate immune cells of the central nervous system, and its involvement in the pa...

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Detalles Bibliográficos
Autores principales: Keaney, James, Gasser, Julien, Gillet, Gaëlle, Scholz, Diana, Kadiu, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707957/
https://www.ncbi.nlm.nih.gov/pubmed/30758770
http://dx.doi.org/10.1007/s11481-019-09839-0

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