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Are k13 and plasmepsin II genes, involved in Plasmodium falciparum resistance to artemisinin derivatives and piperaquine in Southeast Asia, reliable to monitor resistance surveillance in Africa?

Mutations in the propeller domain of Plasmodium falciparum kelch 13 (Pfk13) gene are associated with artemisinin resistance in Southeast Asia. Artemisinin resistance is defined by increased ring survival rate and delayed parasite clearance half-life in patients. Additionally, an amplification of the...

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Detalles Bibliográficos
Autores principales:	Foguim Tsombeng, Francis, Gendrot, Mathieu, Robert, Marie Gladys, Madamet, Marylin, Pradines, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708145/ https://www.ncbi.nlm.nih.gov/pubmed/31443646 http://dx.doi.org/10.1186/s12936-019-2916-6

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