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Ischemia and reperfusion injury following cardioplegic arrest is attenuated by age and testosterone deficiency in male but not female mice

BACKGROUND: Cardiovascular disease increases with age in both sexes. Treatment can require cardiac surgery, where the hearts are pre-treated with protective cardioplegic solution before ischemia and reperfusion (I/R). While endogenous estrogen is beneficial in I/R, whether testosterone is involved i...

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Detalles Bibliográficos
Autores principales:	Ghimire, Anjali, Bisset, Elise S., Howlett, Susan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708213/ https://www.ncbi.nlm.nih.gov/pubmed/31443710 http://dx.doi.org/10.1186/s13293-019-0256-4

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