Eicosapentaenoic acid potentiates the therapeutic effects of adipose tissue-derived mesenchymal stromal cells on lung and distal organ injury in experimental sepsis

BACKGROUND: Even though mesenchymal stromal cells (MSCs) mitigate lung and distal organ damage in experimental polymicrobial sepsis, mortality remains high. We investigated whether preconditioning with eicosapentaenoic acid (EPA) would potentiate MSC actions in experimental sepsis by further decreas...

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Detalles Bibliográficos
Autores principales: Silva, Johnatas D., Lopes-Pacheco, Miquéias, de Castro, Ligia L., Kitoko, Jamil Z., Trivelin, Stefano A., Amorim, Natália R., Capelozzi, Vera L., Morales, Marcelo M., Gutfilen, Bianca, de Souza, Sergio A. L., Weiss, Daniel J., Diaz, Bruno L., Rocco, Patricia R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708232/
https://www.ncbi.nlm.nih.gov/pubmed/31443678
http://dx.doi.org/10.1186/s13287-019-1365-z

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