Intercellular adhesion molecule-1 enhances the therapeutic effects of MSCs in a dextran sulfate sodium-induced colitis models by promoting MSCs homing to murine colons and spleens

BACKGROUND: To investigate the therapeutic effect of intercellular adhesion molecule (ICAM)-1-modified mesenchymal stem cells (MSCs) in a mouse model of inflammatory bowel disease (IBD) induced by dextran sulfate sodium. METHODS: Primary MSCs and ICAM-1-overexpressing MSCs (C3 cells) were generated...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xin, Wang, Qian, Ding, Li, Wang, Yu-Xing, Zhao, Zhi-Dong, Mao, Ning, Wu, Chu-Tse, Wang, Hua, Zhu, Heng, Ning, Shou-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708236/
https://www.ncbi.nlm.nih.gov/pubmed/31443680
http://dx.doi.org/10.1186/s13287-019-1384-9

Ejemplares similares

Ejemplares similares