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Early and reversible changes to the hippocampal proteome in mice on a high-fat diet

BACKGROUND: The rise in global obesity makes it crucial to understand how diet drives obesity-related health conditions, such as premature cognitive decline and Alzheimer’s disease (AD). In AD hippocampal-dependent episodic memory is one of the first types of memory to be impaired. Previous studies...

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Detalles Bibliográficos
Autores principales: McLean, Fiona H., Campbell, Fiona M., Sergi, Domenico, Grant, Christine, Morris, Amanda C., Hay, Elizabeth A., MacKenzie, Alasdair, Mayer, Claus D., Langston, Rosamund F., Williams, Lynda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708244/
https://www.ncbi.nlm.nih.gov/pubmed/31462902
http://dx.doi.org/10.1186/s12986-019-0387-y