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Analysis of lipoprotein transport depletion in Vibrio cholerae using CRISPRi
Genes necessary for the survival or reproduction of a cell are an attractive class of antibiotic targets. Studying essential genes by classical genetics, however, is inherently problematic because it is impossible to knock them out. Here, we screened a set of predicted essential genes for growth inh...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708369/ https://www.ncbi.nlm.nih.gov/pubmed/31371515 http://dx.doi.org/10.1073/pnas.1906158116 |