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Structural Basis for Gating Pore Current in Periodic Paralysis
Potassium-sensitive Hypokalemic and Normokalemic Periodic Paralysis (HypoPP, NormoPP) are inherited skeletal muscle diseases characterized by episodes of flaccid muscle weakness(1,2). They are caused by mutations in one gating charge in an S4 transmembrane segment in the voltage sensor (VS) of volta...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708612/ https://www.ncbi.nlm.nih.gov/pubmed/29769724 http://dx.doi.org/10.1038/s41586-018-0120-4 |