Blunted Evoked Prouroguanylin Endocrine Secretion in Chronic Constipation

Prouroguanylin (ProUGN) in the intestine is cleaved to form uroguanylin (UGN), which stimulates guanylate cyclase C (GUCY2C), inducing cyclic guanosine monophosphate signaling. Paracrine release regulates fluid secretion, contributing to bowel function, whereas endocrine secretion evoked by eating f...

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Detalles Bibliográficos
Autores principales: Waldman, Scott A., Tenenbaum, Renata, Foehl, Henry C., Winkle, Peter, Griffin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708669/
https://www.ncbi.nlm.nih.gov/pubmed/31318728
http://dx.doi.org/10.14309/ctg.0000000000000016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708669/
https://www.ncbi.nlm.nih.gov/pubmed/31318728
http://dx.doi.org/10.14309/ctg.0000000000000016

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