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The necessity of ZSCAN4 for preimplantation development and gene expression of bovine embryos

Zinc finger and SCAN domain containing 4 (Zscan4) is a gene that is specifically expressed during zygotic genome activation (ZGA) in mouse preimplantation embryos, and a reduction of Zscan4 transcripts leads to developmental failure. In mouse embryonic stem cells (ESCs), Zscan4 is expressed transien...

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Detalles Bibliográficos
Autores principales: TAKAHASHI, Kazuki, ROSS, Pablo J., SAWAI, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708851/
https://www.ncbi.nlm.nih.gov/pubmed/31019155
http://dx.doi.org/10.1262/jrd.2019-039