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Age-related changes in DNA methylation levels at CpG sites in bull spermatozoa and in vitro fertilization-derived blastocyst-stage embryos revealed by combined bisulfite restriction analysis

Age-associated methylation changes in genomic DNA have been recently reported in spermatozoa, and these changes can contribute to decline in fertility. In a previous study, we analyzed the genome-wide DNA methylation profiles of bull spermatozoa using a human DNA methylation microarray and identifie...

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Detalles Bibliográficos
Autores principales:	TAKEDA, Kumiko, KOBAYASHI, Eiji, NISHINO, Kagetomo, IMAI, Akira, ADACHI, Hiromichi, HOSHINO, Yoichiro, IWAO, Ken, AKAGI, Satoshi, KANEDA, Masahiro, WATANABE, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708852/ https://www.ncbi.nlm.nih.gov/pubmed/31061296 http://dx.doi.org/10.1262/jrd.2018-146

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