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Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital

To investigate the status of percutaneous coronary intervention (PCI) in elderly patients with acute myocardial infarction (AMI) and analyze the reasons for not receiving PCI. A cohort of 387 consecutive hospitalized AMI patients aged ≥80 years were recruited from 2005 to 2014. Their clinical data w...

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Autores principales: Chen, Liwei, Han, Ling, Luo, Jingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709021/
https://www.ncbi.nlm.nih.gov/pubmed/31335736
http://dx.doi.org/10.1097/MD.0000000000016544
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author Chen, Liwei
Han, Ling
Luo, Jingguang
author_facet Chen, Liwei
Han, Ling
Luo, Jingguang
author_sort Chen, Liwei
collection PubMed
description To investigate the status of percutaneous coronary intervention (PCI) in elderly patients with acute myocardial infarction (AMI) and analyze the reasons for not receiving PCI. A cohort of 387 consecutive hospitalized AMI patients aged ≥80 years were recruited from 2005 to 2014. Their clinical data were collected and analyzed. Among 387 elderly patients with AMI (190 men and 197 women, mean age 84.1 ± 3.9 years), there were 171 patients with ST-elevation myocardial infarction (STEMI) and 216 patients with non-ST-elevation myocardial infarction (NSTEMI). The emergency and elective PCI treatment rate was 40.6% and 12.1%, respectively, in patients with STEMI; and 1% and 18%, respectively, in patients with NSTEMI. PCI treatment rate of elderly AMI patients enrolled after 2009 showed no significant difference compared to that before 2009 (P > .05). The in-hospital mortality decreased significantly in PCI treatment group. After adjustment for age, sex, and other factors, PCI treatment was identified as the independent protective factors for in-hospital mortality (odds ratio = 0.323, 95% confidence interval 0.147–0.710, P = .005). The main influence factors for not receiving PCI treatment were hemorrhage, severe renal dysfunction, infection, or severe anemia-associated complications, whereas delayed treatment was the important reason for patients not undergoing emergency PCI. PCI treatment is the independent protective factor for in-hospital mortality of elderly patients with AMI. Due to various complications, PCI treatment rate is still low in elderly patients with AMI and has not been improved recently. Paying attention to performing PCI treatment for elderly patients with AMI has positive significance.
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spelling pubmed-67090212019-10-01 Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital Chen, Liwei Han, Ling Luo, Jingguang Medicine (Baltimore) Research Article To investigate the status of percutaneous coronary intervention (PCI) in elderly patients with acute myocardial infarction (AMI) and analyze the reasons for not receiving PCI. A cohort of 387 consecutive hospitalized AMI patients aged ≥80 years were recruited from 2005 to 2014. Their clinical data were collected and analyzed. Among 387 elderly patients with AMI (190 men and 197 women, mean age 84.1 ± 3.9 years), there were 171 patients with ST-elevation myocardial infarction (STEMI) and 216 patients with non-ST-elevation myocardial infarction (NSTEMI). The emergency and elective PCI treatment rate was 40.6% and 12.1%, respectively, in patients with STEMI; and 1% and 18%, respectively, in patients with NSTEMI. PCI treatment rate of elderly AMI patients enrolled after 2009 showed no significant difference compared to that before 2009 (P > .05). The in-hospital mortality decreased significantly in PCI treatment group. After adjustment for age, sex, and other factors, PCI treatment was identified as the independent protective factors for in-hospital mortality (odds ratio = 0.323, 95% confidence interval 0.147–0.710, P = .005). The main influence factors for not receiving PCI treatment were hemorrhage, severe renal dysfunction, infection, or severe anemia-associated complications, whereas delayed treatment was the important reason for patients not undergoing emergency PCI. PCI treatment is the independent protective factor for in-hospital mortality of elderly patients with AMI. Due to various complications, PCI treatment rate is still low in elderly patients with AMI and has not been improved recently. Paying attention to performing PCI treatment for elderly patients with AMI has positive significance. Wolters Kluwer Health 2019-07-19 /pmc/articles/PMC6709021/ /pubmed/31335736 http://dx.doi.org/10.1097/MD.0000000000016544 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Research Article
Chen, Liwei
Han, Ling
Luo, Jingguang
Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
title Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
title_full Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
title_fullStr Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
title_full_unstemmed Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
title_short Selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
title_sort selection of percutaneous coronary intervention in elderly patients with acute myocardial infarction in tertiary hospital
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709021/
https://www.ncbi.nlm.nih.gov/pubmed/31335736
http://dx.doi.org/10.1097/MD.0000000000016544
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