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Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources

OBJECTIVE: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study i...

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Autores principales: A., Mozaffari, M., Ghorbani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biomedical Physics and Engineering 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709347/
https://www.ncbi.nlm.nih.gov/pubmed/31531295
http://dx.doi.org/10.31661/jbpe.v0i0.570
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author A., Mozaffari
M., Ghorbani
author_facet A., Mozaffari
M., Ghorbani
author_sort A., Mozaffari
collection PubMed
description OBJECTIVE: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for (60)Co, (137)Cs, (192)Ir and (103)Pd brachytherapy sources by Monte Carlo simulation. METHODS: In this study, (60)Co (model Co0.A86), (137)Cs (model 6520-67), (192)Ir (model BEBIG) and (103)Pd (model OptiSeed) brachytherapy sources were simulated using MCNPX Monte Carlo code. To simulate the sources, the exact geometric characterization of each source was defined in Monte Carlo input programs. Dosimetric parameters including air kerma strength, dose rate constant, radial dose function and anisotropy function were calculated for each source. Each input program was run with sufficient number of particle histories. The maximum type A statistical uncertainty in the simulation of the (60)Co, (137)Cs, (192)Ir and (103)Pd sources, were equal to 4%, 4%, 3.19% and 6.50%, respectively. RESULTS: The results for dosimetry parameters of dose rate constant, radial dose function and anisotropy function for the (60)Co, (137)Cs, (192)Ir and (103)Pd sources in this study demonstrated good agreement with other studies. CONCLUSION: Based on the good agreement between the results of this study and other studies, the TG-43 results for Co0.A86 (60)Co, 67-65200 (137)Cs, BEBIG (192)Ir and OptiSeed (103)Pd sources are validated and can be used as input data in treatment planning systems (TPSs) and to validate the TPS calculations.
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spelling pubmed-67093472019-09-17 Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources A., Mozaffari M., Ghorbani J Biomed Phys Eng Original Article OBJECTIVE: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for (60)Co, (137)Cs, (192)Ir and (103)Pd brachytherapy sources by Monte Carlo simulation. METHODS: In this study, (60)Co (model Co0.A86), (137)Cs (model 6520-67), (192)Ir (model BEBIG) and (103)Pd (model OptiSeed) brachytherapy sources were simulated using MCNPX Monte Carlo code. To simulate the sources, the exact geometric characterization of each source was defined in Monte Carlo input programs. Dosimetric parameters including air kerma strength, dose rate constant, radial dose function and anisotropy function were calculated for each source. Each input program was run with sufficient number of particle histories. The maximum type A statistical uncertainty in the simulation of the (60)Co, (137)Cs, (192)Ir and (103)Pd sources, were equal to 4%, 4%, 3.19% and 6.50%, respectively. RESULTS: The results for dosimetry parameters of dose rate constant, radial dose function and anisotropy function for the (60)Co, (137)Cs, (192)Ir and (103)Pd sources in this study demonstrated good agreement with other studies. CONCLUSION: Based on the good agreement between the results of this study and other studies, the TG-43 results for Co0.A86 (60)Co, 67-65200 (137)Cs, BEBIG (192)Ir and OptiSeed (103)Pd sources are validated and can be used as input data in treatment planning systems (TPSs) and to validate the TPS calculations. Journal of Biomedical Physics and Engineering 2019-08-01 /pmc/articles/PMC6709347/ /pubmed/31531295 http://dx.doi.org/10.31661/jbpe.v0i0.570 Text en Copyright: © Journal of Biomedical Physics and Engineering http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
A., Mozaffari
M., Ghorbani
Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
title Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
title_full Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
title_fullStr Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
title_full_unstemmed Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
title_short Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
title_sort determination of tg-43 dosimetric parameters for photon emitting brachytherapy sources
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709347/
https://www.ncbi.nlm.nih.gov/pubmed/31531295
http://dx.doi.org/10.31661/jbpe.v0i0.570
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