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7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line
Oxysterols are 27-carbon oxidation products of cholesterol metabolism. Oxysterols possess several biological actions, including the promotion of cell death. Here, we examined the ability of 7-ketocholesterol (7-KC), cholestane-3β-5α-6β-triol (triol), and a mixture of 5α-cholestane-3β,6β-diol and 5α-...
Autores principales: | Levy, Debora, de Melo, Thatiana Correa, Oliveira, Beatriz A., Paz, Jessica L., de Freitas, Fabio A., Reichert, Cadiele O., Rodrigues, Alessandro, Bydlowski, Sergio P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709374/ https://www.ncbi.nlm.nih.gov/pubmed/31463370 http://dx.doi.org/10.1016/j.bbrep.2018.12.008 |
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