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Novel gain-of-function mutation of TRPV4 associated with accelerated chondrogenic differentiation of dental pulp stem cells derived from a patient with metatropic dysplasia

Metatropic dysplasia is a congenital skeletal dysplasia characterized by severe platyspondyly, dumbbell-like deformity of long tubular bones, and progressive kyphoscoliosis with growth. It is caused by mutations in the gene TRPV4, encoding the transient receptor potential vanilloid 4, which acts as...

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Detalles Bibliográficos
Autores principales:	Nonaka, Kentaro, Han, Xu, Kato, Hiroki, Sato, Hiroshi, Yamaza, Haruyoshi, Hirofuji, Yuta, Masuda, Keiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709385/ https://www.ncbi.nlm.nih.gov/pubmed/31463371 http://dx.doi.org/10.1016/j.bbrep.2019.100648

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