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A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare

Lemierre syndrome develops in healthy young patients as a result of bacteremia after oral cavity infection. It causes thrombophlebitis in the internal jugular vein. Infection can easily occur during immunosuppressive treatment in patients with systemic lupus erythematosus and become severe. We prese...

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Autores principales: Fujii, Teruhiro, Iwabuchi, Yuko, Moriyama, Takahito, Uchida, Keiko, Nitta, Kosaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709436/
https://www.ncbi.nlm.nih.gov/pubmed/31489196
http://dx.doi.org/10.1177/2050313X19871782
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author Fujii, Teruhiro
Iwabuchi, Yuko
Moriyama, Takahito
Uchida, Keiko
Nitta, Kosaku
author_facet Fujii, Teruhiro
Iwabuchi, Yuko
Moriyama, Takahito
Uchida, Keiko
Nitta, Kosaku
author_sort Fujii, Teruhiro
collection PubMed
description Lemierre syndrome develops in healthy young patients as a result of bacteremia after oral cavity infection. It causes thrombophlebitis in the internal jugular vein. Infection can easily occur during immunosuppressive treatment in patients with systemic lupus erythematosus and become severe. We present a case of Lemierre syndrome in a patient with systemic lupus erythematosus. A 56-year-old woman presented with fever, left lower toothache, and skin symptoms from the left neck to the anterior chest. Clinical presentation and laboratory investigations revealed Lemierre syndrome. The inflammation and thrombus disappeared with antibiotic and anticoagulant therapies. However, transient hypocomplementemia and elevated antinuclear antibody levels were observed during treatment; therefore, a concomitant systemic lupus erythematosus flare was considered. In systemic lupus erythematosus patients with Lemierre syndrome, complement and antinuclear antibody levels are modified, so other indicators should be precisely evaluated, such as levels of urinary protein, sediment, serum creatinine and anti-dsDNA antibody, and systemic lupus erythematosus disease activity index.
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spelling pubmed-67094362019-09-05 A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare Fujii, Teruhiro Iwabuchi, Yuko Moriyama, Takahito Uchida, Keiko Nitta, Kosaku SAGE Open Med Case Rep Case Report Lemierre syndrome develops in healthy young patients as a result of bacteremia after oral cavity infection. It causes thrombophlebitis in the internal jugular vein. Infection can easily occur during immunosuppressive treatment in patients with systemic lupus erythematosus and become severe. We present a case of Lemierre syndrome in a patient with systemic lupus erythematosus. A 56-year-old woman presented with fever, left lower toothache, and skin symptoms from the left neck to the anterior chest. Clinical presentation and laboratory investigations revealed Lemierre syndrome. The inflammation and thrombus disappeared with antibiotic and anticoagulant therapies. However, transient hypocomplementemia and elevated antinuclear antibody levels were observed during treatment; therefore, a concomitant systemic lupus erythematosus flare was considered. In systemic lupus erythematosus patients with Lemierre syndrome, complement and antinuclear antibody levels are modified, so other indicators should be precisely evaluated, such as levels of urinary protein, sediment, serum creatinine and anti-dsDNA antibody, and systemic lupus erythematosus disease activity index. SAGE Publications 2019-08-22 /pmc/articles/PMC6709436/ /pubmed/31489196 http://dx.doi.org/10.1177/2050313X19871782 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Fujii, Teruhiro
Iwabuchi, Yuko
Moriyama, Takahito
Uchida, Keiko
Nitta, Kosaku
A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
title A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
title_full A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
title_fullStr A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
title_full_unstemmed A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
title_short A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
title_sort case of lemierre syndrome combined with a suspected systemic lupus erythematosus flare
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709436/
https://www.ncbi.nlm.nih.gov/pubmed/31489196
http://dx.doi.org/10.1177/2050313X19871782
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