Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension

We show that spironolactone use was associated with an increased rate of all-cause hospitalizations, but no difference in hospitalizations for heart failure or pulmonary arterial hypertension, in patients with World Health Organization Group 1 pulmonary arterial hypertension. A possible reason for t...

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Detalles Bibliográficos
Autores principales: Corkish, Morgan E., Devine, Lauren T., Clarke, Megan M., Murray, Brian P., Rose-Jones, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709444/
https://www.ncbi.nlm.nih.gov/pubmed/31319761
http://dx.doi.org/10.1177/2045894019868422
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author Corkish, Morgan E.
Devine, Lauren T.
Clarke, Megan M.
Murray, Brian P.
Rose-Jones, Lisa J.
author_facet Corkish, Morgan E.
Devine, Lauren T.
Clarke, Megan M.
Murray, Brian P.
Rose-Jones, Lisa J.
author_sort Corkish, Morgan E.
collection PubMed
description We show that spironolactone use was associated with an increased rate of all-cause hospitalizations, but no difference in hospitalizations for heart failure or pulmonary arterial hypertension, in patients with World Health Organization Group 1 pulmonary arterial hypertension. A possible reason for this finding is confounding from retrospective study design.
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spelling pubmed-67094442019-09-05 Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension Corkish, Morgan E. Devine, Lauren T. Clarke, Megan M. Murray, Brian P. Rose-Jones, Lisa J. Pulm Circ Research Letter We show that spironolactone use was associated with an increased rate of all-cause hospitalizations, but no difference in hospitalizations for heart failure or pulmonary arterial hypertension, in patients with World Health Organization Group 1 pulmonary arterial hypertension. A possible reason for this finding is confounding from retrospective study design. SAGE Publications 2019-08-22 /pmc/articles/PMC6709444/ /pubmed/31319761 http://dx.doi.org/10.1177/2045894019868422 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Research Letter
Corkish, Morgan E.
Devine, Lauren T.
Clarke, Megan M.
Murray, Brian P.
Rose-Jones, Lisa J.
Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
title Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
title_full Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
title_fullStr Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
title_full_unstemmed Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
title_short Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
title_sort rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709444/
https://www.ncbi.nlm.nih.gov/pubmed/31319761
http://dx.doi.org/10.1177/2045894019868422
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