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In Vivo Pharmacodynamic Study of Cefiderocol, a Novel Parenteral Siderophore Cephalosporin, in Murine Thigh and Lung Infection Models
The pharmacokinetic (PK) and pharmacodynamic (PD) parameters which correlated with the in vivo efficacy of cefiderocol were evaluated using neutropenic murine thigh and lung infection models in which the infections were caused by a variety of Gram-negative bacilli. The dose fractionation study using...
Autores principales: | Nakamura, Rio, Ito-Horiyama, Tsukasa, Takemura, Miki, Toba, Shinsuke, Matsumoto, Shuhei, Ikehara, Tatsuya, Tsuji, Masakatsu, Sato, Takafumi, Yamano, Yoshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709502/ https://www.ncbi.nlm.nih.gov/pubmed/31262762 http://dx.doi.org/10.1128/AAC.02031-18 |
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