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Therapeutic targets of hypercholesterolemia: HMGCR and LDLR

Cholesterol homeostasis is critical and necessary for the body’s functions. Hypercholesterolemia can lead to significant clinical problems, such as cardiovascular disease (CVD). 3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) and low–density lipoprotein cholesterol receptor (LDLR) are major...

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Detalles Bibliográficos
Autores principales:	Ma, Shizhan, Sun, Wenxiu, Gao, Ling, Liu, Shudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709517/ https://www.ncbi.nlm.nih.gov/pubmed/31686875 http://dx.doi.org/10.2147/DMSO.S219013

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