Safety and Efficacy of Bis-Glyceryl Ascorbate (Amitose DGA) to Prevent Hand-Foot Skin Reaction in Patients With Renal Cell Carcinoma Receiving Sunitinib Therapy: Protocol for a Phase I/II, Uncontrolled, Single-Arm, Open-Label Trial

BACKGROUND: Hand-foot skin reaction (HFSR) is a serious side effect induced by multiple-tyrosine kinase inhibitors (TKIs). HFSR can cause treatment interruption or decreased dosing. HFSR also markedly decreases quality of life and is associated with the therapeutic efficacy of multiple-TKIs. Therefo...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kazuhiro, Ioroi, Takeshi, Harada, Kenichi, Nishiyama, Satoshi, Nishigori, Chikako, Yano, Ikuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2019
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709566/
https://www.ncbi.nlm.nih.gov/pubmed/31407671
http://dx.doi.org/10.2196/14636

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