Cargando…

Atorvastatin Induces Hepatotoxicity in Diabetic Rats via Oxidative Stress, Inflammation, and Anti-Apoptotic Pathway

BACKGROUND: Patients with diabetes mellitus (DM) commonly receive statins to suppress vulnerability to adverse cardiovascular events. It has been clinically proven that hepatotoxicity is one of the most severe adverse effects of statins. MATERIAL/METHODS: We constructed diabetic rat models by feedin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Hanqing, Liu, Zhongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709644/
https://www.ncbi.nlm.nih.gov/pubmed/31420530
http://dx.doi.org/10.12659/MSM.915790