Esomeprazole alleviates the damage to stress ulcer in rats through not only its antisecretory effect but its antioxidant effect by inactivating the p38 MAPK and NF-κB signaling pathways

BACKGROUND: Stress ulcer is a severe complication in critically ill patients and causes a high mortality. The proton pump inhibitor esomeprazole is widely applied in the treatment of stress ulcers because of its powerful acid suppression ability. However, the mechanism of stress ulcer and the precis...

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Detalles Bibliográficos
Autores principales: Xie, Wei, Huang, Xielin, Chen, Renpin, Chen, Ruru, Li, Tang, Wu, Wei, Huang, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709796/
https://www.ncbi.nlm.nih.gov/pubmed/31686780
http://dx.doi.org/10.2147/DDDT.S193641

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